| Identification | Back Directory | [Name]
Cyclohexanecarboxamide, N-[3-[(2,5-dimethylphenyl)methoxy]-4-[methyl(methylsulfonyl)amino]phenyl]- | [CAS]
1021926-22-6 | [Synonyms]
JCC76
Cyclohexanecarboxamide, N-[3-[(2,5-dimethylphenyl)methoxy]-4-[methyl(methylsulfonyl)amino]phenyl]- | [Molecular Formula]
C24H32N2O4S | [MOL File]
1021926-22-6.mol | [Molecular Weight]
444.59 |
| Chemical Properties | Back Directory | [density ]
1.230±0.06 g/cm3(Predicted) | [storage temp. ]
2-8°C | [solubility ]
DMSO: 25mg/mL | [form ]
solid | [pka]
13.92±0.70(Predicted) | [color ]
off-white |
| Hazard Information | Back Directory | [Uses]
JCC76 is the derivative of Nimesulide (HY-B0363). JCC76 inhibits the proliferation of Her2 positive breast cancer cell SKBR-3 with IC50 of 3.43 μM[1]. | [References]
[1] Zhong B, et al., Design and synthesis of a biotinylated probe of COX-2 inhibitor nimesulide analog JCC76. Bioorg Med Chem Lett. 2011 Sep 15;21(18):5324-7. DOI:10.1016/j.bmcl.2011.07.025 |
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| Company Name: |
Merck KGaA
|
| Tel: |
21-20338288 |
| Website: |
www.sigmaaldrich.cn |
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