| Identification | Back Directory | [Name]
3-(4-Phenoxy-phenyl)-1-piperidin-3-yl-1H-pyrazolo[3,4-d]pyriMidin-4-ylaMine | [CAS]
1022150-12-4 | [Synonyms]
ibrutinib N-1
Ilutinib impurity 18
Ibrutinib Impurity 18
4-d]pyriMidin-4-ylaMine
Ibrutinib intermediate 1
Ibrutinib intermeidate N-1
Btk inhibitor 1 (R enantioMer)
Ibrutinib N-Desacryloyl Impurity
Ibrutinib (PCI-32765) Intermediates
(S)-Ibrutinib N-Desacryloyl Impurity
(R)-3-(4-phenoxyphenyl)-1-(piperidin-3-yl)
3-(4-Phenoxy-phenyl)-1-piperidin-3-yl-1H-pyrazolo[3
3-(4-phenoxyphenyl)-1-(3-piperidyl)pyrazolo[3,4-d]pyrimidin-...
3-(4-phenoxyphenyl)-1-(3-piperidyl)pyrazolo[3,4-d]pyriMidin-4-aMine
3-(4-Phenoxyphenyl)-1-(piperidin-3-yl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine
3-(4-Phenoxy-phenyl)-1-piperidin-3-yl-1H-pyrazolo[3,4-d]pyriMidin-4-ylaMine
3-(4-phenoxypheny)1-((3R)-3-pipeidinyl)-1H-pyrazolo[3.4-dleyrimidin-4-amine
(R)-3-(4-phenoxyphenyl)-1-(piperidin-3-yl)-1H-pyrazolo[3,4-d]pyriMidin-4-aMi
3-(4-phenoxyphenyl)-1-(3R)-3-piperidinyl-1H-Pyrazolo[3,4-d]pyrimidin-4-amine
(R)-4-Amino-3-(4-phenoxyphenyl)-1-(3-piperidyl)-1H-pyrazolo[3,4-d]pyrimidine
(R)-3-(4-phenoxyphenyl)-1-(piperidin-3-yl)-1H-pyrazolo[3,4-d]pyriMidin-4-aMine
(R)-3-(4-Phenoxyphenyl)-1
-（piperidin-3-yl）pyrazolo [3,4-D]pyrimidin-4-ylamine
1H-Pyrazolo[3,4-d]pyrimidin-4-amine, 3-(4-phenoxyphenyl)-1-(3R)-3-piperidinyl-
3-(4-phenoxyphenyl)-1-[(3R)-piperidin-3-yl]-1H-pyrazolo[3,4-d]pyrimidin-4-amine
(R)-3-(4-Phenoxy-phenyl)-1-piperidin-3-yl-1H-pyrazolo[3,4-d]pyrimidin-4-ylamine
3-(4-Phenoxy-phenyl)-1-(R)-piperidin-3-yl-1H-pyrazolo[3,4-d]pyriMidin-4-ylaMine
(R)-3-(4-phenoxyphenyl)-1-(piperidine-3-yl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine
(R)-3-(4-phenoxyphenyl)-1-(piperidine-3-yl)-1H-pyrazolo[3,4-d]pyrimidine-4-amine
3- (4-phenoxy-phenyl) -1-piperidine-3-yl-1H-pyrazolium [3, 4-D] pyrimidin-4-ylamine
(R)-3-(4-phenoxyphenyl)-1-(piperidine-3-yl)-1 H- pyrazole [3,4- d] pyrimidine-4-amine
3-(4-Phenoxy-phenyl)-1-piperidin-3-yl-1H-pyrazolo[3,4-d]pyriMidin-4-ylaMine 1022150-12-4
(R)-3-(4-Phenoxyphenyl)-1-(piperidin-3-yl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine 1022150-12-4
2-Propenamide, N-[4-[(3-chloro-4-fluorophenyl)amino]-7-[3-methyl-3-(4-methyl-1-piperazinyl)
(R)-3-(4-phenoxyphenyl)-1-(piperidin-3-yl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine hydrochloride
TIANFUCHEM--1022150-12-4---3-(4-Phenoxy-phenyl)-1-piperidin-3-yl-1H-pyrazolo[3,4-d]pyriMidin-4-ylaMine
3-(4-Phenoxy-phenyl)-1-piperidin-3-yl-1H-pyrazolo[3,4-d]pyrimidin-4-ylamine(Btk inhibitor 1 R enantiomer)
Ibrutinib N-1 (R)-3-(4-phenoxyphenyl)-1-(piperidin-3-yl)-1H-pyrazolo[3,4-d]pyriMidin-4-aMine | [EINECS(EC#)]
200-001-8 | [Molecular Formula]
C22H22N6O | [MDL Number]
MFCD19443124 | [MOL File]
1022150-12-4.mol | [Molecular Weight]
386.45 |
| Chemical Properties | Back Directory | [Melting point ]
133-136oC | [Boiling point ]
626.3±55.0 °C(Predicted) | [density ]
1.39±0.1 g/cm3(Predicted) | [storage temp. ]
Keep in dark place,Inert atmosphere,2-8°C | [solubility ]
DMSO (Slightly), Methanol (Slightly) | [form ]
Solid | [pka]
9.00±0.10(Predicted) | [color ]
White to Pale Yellow |
| Hazard Information | Back Directory | [Description]
IBT6A is a Btk kinase inhibitor. This compound is a precurser for the manufacture of ibrutinib. | [Uses]
(R)-3-(4-Phenoxyphenyl)-1-(piperidin-3-yl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine is an intermediate used to prepare pyrazolo-pyrimidine compounds as inhibitors of Bruton''s tyrosine kinase. It is also an intermediate for Ibrutinib (I124970) derivatives. |
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