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10233-81-5

10233-81-5 Structure

10233-81-5 Structure
IdentificationBack Directory
[Name]

2-(Dimethylamino)-N-[11-hydroxy-3-isopropyl-5,8-dioxo-7-benzyl-2-oxa-6,9-diazabicyclo[10.2.2]hexadeca-12,14(1),15-trien-4-yl]-3-methylpentanamide
[CAS]

10233-81-5
[Synonyms]

Pandamine
2-(Dimethylamino)-N-[11-hydroxy-3-isopropyl-5,8-dioxo-7-benzyl-2-oxa-6,9-diazabicyclo[10.2.2]hexadeca-12,14(1),15-trien-4-yl]-3-methylpentanamide
[Molecular Formula]

C31H44N4O5
[MOL File]

10233-81-5.mol
Chemical PropertiesBack Directory
[Melting point ]

256°C
Hazard InformationBack Directory
[Description]

An alkaloid of the peptide class, this base if found in Panda oleosa Pierre. It is best crystallized from AcOEt when it yields clusters of colourless crystals. It has [α]D - 103° (c 0.5, CHCI3) and gives a laevorotatory hydrochloride, m.p. 235°C (dec.); [α]D - 77° (c 1.0, MeOH). The presence of a hydroxyl group is shown by the formation of the O-acetate, m.p. 30S-7°C; [α]D - 98° (c 0.5, pyridine), giving a hydrochloride, m.p. 280°C (dec.); [α]D - 89° (c 1.0, MeOH). Three of the nitrogen atoms are present as amide groups, the fourth being a dimethylamino group.
[Uses]

Pandamine is a natural alkaloid that can be extracted from Panda oleosa[1].
[Definition]

ChEBI: Pandamine is a cyclic peptide.
[References]

Pais et al., Bull. Soc. Chim. Fr., 817 (1964)
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