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1027105-06-1

1027105-06-1 Structure

1027105-06-1 Structure
IdentificationBack Directory
[Name]

S-Thanatin
[CAS]

1027105-06-1
[Synonyms]

S-Thanatin
[Molecular Formula]

C102H177N35O27S3
[MOL File]

1027105-06-1.mol
[Molecular Weight]

2421.92
Chemical PropertiesBack Directory
[density ]

1.50±0.1 g/cm3(Temp: 20 °C; Press: 760 Torr)(predicted)
[Sequence]

Gly-Ser-Lys-Lys-Pro-Val-Pro-Ile-Ile-Tyr-Cys-Asn-Arg-Arg-Ser-Gly-Lys-Cys-Gln-Arg-Met
Hazard InformationBack Directory
[Uses]

S-Thanatin is an insect antimicrobial peptide with potent broad-spectrum antibacterial activity. S-Thanatin can inhibit the activity of Gram-negative bacteria, Gram-positive bacteria, and fungi, without cytotoxicity. The antibacterial activity of S-Thanatin is not affected by PH value, but monovalent cations (Na+/K+) can reduce its antibacterial activity against Gram-negative bacteria in a dose-dependent manner[1].
[References]

[1] Wu G, et al. Effects of cations and pH on antimicrobial activity of thanatin and s-thanatin against Escherichia coli ATCC25922 and B. subtilis ATCC 21332[J]. Nature Precedings, 2008: 1-1. DOI:10.1007/s00284-008-9241-6
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