| Identification | Back Directory | [Name]
1-[[(6R,7R)-7-[[(2Z)-2-(2-AMino-4-thiazolyl)-2-[[2-(1,1-diMethylethoxy)-1,1-diMethyl-2-oxoethoxy]iMino]acetyl]aMino]-2-carboxy-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-en-3-yl]Methyl]pyridiniuM Inner Salt | [CAS]
102772-66-7 | [Synonyms]
Ceftazidime EP Imp E
CeftazidiMe t-Butyl Ester
Ceftazidime Ep Impurity E
Ceftazidime Impurity D(EP)
Ceftazidime tert-butyl ester
Ceftazidime N-2 Intermediate
Ceftazidime Impurity 5(Ceftazidime EP Impurity E)
Ceftazidime Impurity E (EP) (Ceftazidime t-Butyl Ester )
(6R,7R)-7-((Z)-2-(2-aminothiazol-4-yl)-2-(((1-(tert-butoxy)-2-methyl-1-oxopropan-2-yl)oxy)imino)acetamido)-8-oxo-3-(pyridin-1-ium-1-ylmethyl)-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate
1-[[(6R,7R)-7-[[(2Z)-2-(2-AMino-4-thiazolyl)-2-[[2-(1,1-diMethylethoxy)-1,1-diMethyl-2-oxoethoxy]iMino]acetyl]aMino]-2-carboxy-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-en-3-yl]Methyl]pyridiniuM Inner Salt
Ceftazidime impurity 5/Ceftazidime EP Impurity E/(6R,7R)-7-[[(2Z)-2-(2-aminothiazol-4-yl)-2-[[2-(1,1-dimethylethoxy)-1,1-dimethyl-2-oxoethoxy]imino]acetyl]amino]-8-oxo-3-[(1-pyridinio)methyl]-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate | [Molecular Formula]
C26H30N6O7S2 | [MDL Number]
MFCD21363485 | [MOL File]
102772-66-7.mol | [Molecular Weight]
602.682 |
| Chemical Properties | Back Directory | [Melting point ]
>195°C (dec.) | [storage temp. ]
Hygroscopic, -20°C Freezer, Under inert atmosphere | [solubility ]
DMSO (Slightly), Methanol (Slightly) | [form ]
Solid | [color ]
Off-Whte to Brown | [InChIKey]
KRTGQDGIPNXUGP-UTMOZWIMNA-N | [SMILES]
C(C1=C(CS[C@]2([H])[C@H](NC(=O)/C(/C3N=C(N)SC=3)=N\OC(C)(C)C(=O)OC(C)(C)C)C(=O)N12)C[N+]1=CC=CC=C1)(=O)[O-] |&1:5,7,r| |
| Hazard Information | Back Directory | [Uses]
Ceftazidime t-Butyl ester is an impurity of Ceftazidime (C244100). Ceftazidime impurity C. | [Synthesis]
A preparation method of 1-[[(6R,7R)-7-[[(2Z)-2-(2-AMino-4-thiazolyl)-2-[[2-(1,1-diMethylethoxy)-1,1-diMethyl-2-oxoethoxy]iMino]acetyl]aMino]-2-carboxy-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-en-3-yl]Methyl]pyridiniuM Inner Salt: add trichloromethane 520ml i |
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