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102772-66-7

102772-66-7 Structure

102772-66-7 Structure
IdentificationBack Directory
[Name]

1-[[(6R,7R)-7-[[(2Z)-2-(2-AMino-4-thiazolyl)-2-[[2-(1,1-diMethylethoxy)-1,1-diMethyl-2-oxoethoxy]iMino]acetyl]aMino]-2-carboxy-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-en-3-yl]Methyl]pyridiniuM Inner Salt
[CAS]

102772-66-7
[Synonyms]

Ceftazidime EP Imp E
CeftazidiMe t-Butyl Ester
Ceftazidime Ep Impurity E
Ceftazidime Impurity D(EP)
Ceftazidime tert-butyl ester
Ceftazidime N-2 Intermediate
Ceftazidime Impurity 5(Ceftazidime EP Impurity E)
Ceftazidime Impurity E (EP) (Ceftazidime t-Butyl Ester )
(6R,7R)-7-((Z)-2-(2-aminothiazol-4-yl)-2-(((1-(tert-butoxy)-2-methyl-1-oxopropan-2-yl)oxy)imino)acetamido)-8-oxo-3-(pyridin-1-ium-1-ylmethyl)-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate
1-[[(6R,7R)-7-[[(2Z)-2-(2-AMino-4-thiazolyl)-2-[[2-(1,1-diMethylethoxy)-1,1-diMethyl-2-oxoethoxy]iMino]acetyl]aMino]-2-carboxy-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-en-3-yl]Methyl]pyridiniuM Inner Salt
Ceftazidime impurity 5/Ceftazidime EP Impurity E/(6R,7R)-7-[[(2Z)-2-(2-aminothiazol-4-yl)-2-[[2-(1,1-dimethylethoxy)-1,1-dimethyl-2-oxoethoxy]imino]acetyl]amino]-8-oxo-3-[(1-pyridinio)methyl]-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate
[Molecular Formula]

C26H30N6O7S2
[MDL Number]

MFCD21363485
[MOL File]

102772-66-7.mol
[Molecular Weight]

602.682
Chemical PropertiesBack Directory
[Melting point ]

>195°C (dec.)
[storage temp. ]

Hygroscopic, -20°C Freezer, Under inert atmosphere
[solubility ]

DMSO (Slightly), Methanol (Slightly)
[form ]

Solid
[color ]

Off-Whte to Brown
[InChIKey]

KRTGQDGIPNXUGP-UTMOZWIMNA-N
[SMILES]

C(C1=C(CS[C@]2([H])[C@H](NC(=O)/C(/C3N=C(N)SC=3)=N\OC(C)(C)C(=O)OC(C)(C)C)C(=O)N12)C[N+]1=CC=CC=C1)(=O)[O-] |&1:5,7,r|
Safety DataBack Directory
[Symbol(GHS) ]

Health Hazard (GHS08)
GHS08
[Signal word ]

Danger
[Hazard statements ]

H317-H334
[Precautionary statements ]

P261-P285-P304+P341-P342+P311-P501-P261-P272-P280-P302+P352-P333+P313-P321-P363-P501
[REACH Registrations]

Active
Hazard InformationBack Directory
[Uses]

Ceftazidime t-Butyl ester is an impurity of Ceftazidime (C244100). Ceftazidime impurity C.
[Synthesis]

A preparation method of 1-[[(6R,7R)-7-[[(2Z)-2-(2-AMino-4-thiazolyl)-2-[[2-(1,1-diMethylethoxy)-1,1-diMethyl-2-oxoethoxy]iMino]acetyl]aMino]-2-carboxy-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-en-3-yl]Methyl]pyridiniuM Inner Salt: add trichloromethane 520ml i
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