| Identification | Back Directory | [Name]
9H-Purin-6-amine, 9-(2-deoxy-4-C-ethynyl-2-fluoro-β-D-arabinofuranosyl)-2-fluoro- | [CAS]
1030595-07-3 | [Synonyms]
9-(2-Deoxy-4-C-ethynyl-2-fluoro-β-D-arabinofuranosyl)-2-fluoro-9H-purin-6-amine
9H-Purin-6-amine, 9-(2-deoxy-4-C-ethynyl-2-fluoro-β-D-arabinofuranosyl)-2-fluoro- | [Molecular Formula]
C12H11F2N5O3 | [MOL File]
1030595-07-3.mol | [Molecular Weight]
311.24 |
| Chemical Properties | Back Directory | [Boiling point ]
670.7±65.0 °C(Predicted) | [density ]
1.79±0.1 g/cm3(Predicted) | [form ]
Solid | [pka]
11.92±0.70(Predicted) | [color ]
White to off-white |
| Hazard Information | Back Directory | [Uses]
CL-197 is an orally active and long-acting purine anti-HIV nucleoside reverse transcriptase inhibitor (NRTI). CL-197 has potential effect on the research of viral, oncological and cerebrovascular diseases[1]. CL-197 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups. | [References]
[1] Hou J, et al. 4'-Ethynyl-2'-deoxy-2'-β-fluoro-2-fluoroadenosine: A Highly Potent and Orally Available Clinical Candidate for the Treatment of HIV-1 Infection. J Med Chem. 2023 Aug 24;66(16):11282-11293. DOI:10.1021/acs.jmedchem.3c00761 |
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| Company Name: |
NewCan Biotech Limited
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| Tel: |
+86-0571-86912261 +86-15658003402 |
| Website: |
https://www.newcanbio.com/ |
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