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103342-82-1

103342-82-1 Structure

103342-82-1 Structure
IdentificationBack Directory
[Name]

5-(2-FLUOROPHENYL)-1,3-DIHYDRO-3-(1H-INDOL-3-YLMETHYL)-1-METHYL-2H-1,4-BENZODIAZEPIN-2-ONE
[CAS]

103342-82-1
[Synonyms]

373
L-364,373
L364,373,L 364,373
Devazepide Impurity 1 (L-364373)
5-(2-FLUOROPHENYL)-1,3-DIHYDRO-3-(1H-INDOL-3-YLMETHYL)-1-METHYL-2H-1,4-BENZODIAZEPIN-2-ONE
2H-1,4-Benzodiazepin-2-one, 5-(2-fluorophenyl)-1,3-dihydro-3-(1H-indol-3-ylmethyl)-1-methyl-, (3R)-
[Molecular Formula]

C25H20FN3O
[MDL Number]

MFCD10687096
[MOL File]

103342-82-1.mol
[Molecular Weight]

397.44
Chemical PropertiesBack Directory
[storage temp. ]

Store at +4°C
[solubility ]

Soluble to 100 mM in DMSO
[form ]

Powder
[color ]

White to off-white
Hazard InformationBack Directory
[Uses]

L-364,373 is a KCNQ1/mink channels activator.
[Definition]

ChEBI: R-L3 is a benzodiazepine.
[Biological Activity]

Activator of KCNQ1 (K V LQT1) channels. Activates the cardiac I Ks current that decreases action potential duration (APD) in cardiac myocytes.
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