ChemicalBook--->CAS DataBase List--->103420-77-5

103420-77-5

103420-77-5 Structure

103420-77-5 Structure
IdentificationBack Directory
[Name]

DEVAZEPIDE
[CAS]

103420-77-5
[Synonyms]

MK-329
L-364718
DEVAZEPIDE
EVAZEPIDE, PANOS
(3S)-1-Methyl-3-[(1H-indol-2-yl)carbonylamino]-5-phenyl-1H-1,4-benzodiazepin-2(3H)-one
(S)-N-(2,3-Dihydro-1-methyl-2-oxo-5-phenyl-1H-1,4-benzodiazepin-3-yl)indole-2-carboxamide
N-[(3S)-2,3-DIHYDRO-1-METHYL-2-OXO-5-PHENYL-1H-1,4-BENZODIAZEPIN-3-YL]-1H-INDOLE-2-CARBOXAMIDE
1H-Indole-2-carboxamide, N-[(3S)-2,3-dihydro-1-methyl-2-oxo-5-phenyl-1H-1,4-benzodiazepin-3-yl]-
[Molecular Formula]

C25H20N4O2
[MDL Number]

MFCD00864500
[MOL File]

103420-77-5.mol
[Molecular Weight]

408.45
Chemical PropertiesBack Directory
[Boiling point ]

758.6±60.0 °C(Predicted)
[density ]

1.31±0.1 g/cm3(Predicted)
[storage temp. ]

2-8°C
[solubility ]

DMSO: >5mg/mL
[form ]

powder
[pka]

13.25±0.40(Predicted)
[color ]

white to off-white
Safety DataBack Directory
[Hazard Codes ]

T+
[Risk Statements ]

28
[Safety Statements ]

28-36/37-45
[RIDADR ]

UN 2811 6.1 / PGI
[WGK Germany ]

3
[RTECS ]

NL5994460
Hazard InformationBack Directory
[Uses]

Antagonist (cholecystokinin).
[Definition]

ChEBI: An indolecarboxamide obtained by formal condensation of the carboxy group of indole-2-carboxylic acid with the exocyclic amino group of (3S)-3-amino-1-methyl-5-phenyl-1,3-dihydro-1,4-benzodiazepin-2-one. A cholecystokinin antagonist used f r treatment of gastrointestinal disorders.
[General Description]

Devazepide is derived from asperlicin by chemical modification and has the benzodiazepine backbone.
[Biochem/physiol Actions]

Devazepide is a CCK1 (CCK-A) receptor antagonist and a CCK8 antagonist.
[storage]

Store at +4°C
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