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103439-17-4

103439-17-4 Structure

103439-17-4 Structure
IdentificationBack Directory
[Name]

(+/-)-1-AMINO-TRANS-3-PHOSPHONO-CYCLOPEN TANE CARBO
[CAS]

103439-17-4
[Synonyms]

Z-Cyclopentyl-AP4
(+/-)-1-AMINO-TRANS-3-PHOSPHONO-CYCLOPEN TANE CARBO
(+/-)-1-AMINO-TRANS-3-PHOSPHONO-CYCLOPEN TANE CARBO
Z-Cyclopentyl-AP-4,ZCyclopentylAP4,Z Cyclopentyl AP4
cis-(±)-1-Amino-3-phosphonocyclopentanecarboxylicacid
Cyclopentanecarboxylic acid, 1-amino-3-phosphono-, (1R,3S)-rel-
[Molecular Formula]

C6H12NO5P
[MOL File]

103439-17-4.mol
[Molecular Weight]

209.14
Chemical PropertiesBack Directory
[storage temp. ]

Store at +4°C
[solubility ]

Soluble to 50 mM in 1.1eq. NaOH
[form ]

Powder
Hazard InformationBack Directory
[Uses]

Z-Cyclopentyl-AP4 is a Group III mGluR (mGluR-4,6) agonist.
[Biological Activity]

Group III mGlu receptor agonist that exhibits higher potency at mGlu 4 than mGlu 8 (EC 50 values are 49 and 124 μ M respectively) with no activity at mGlu 7 . Selectively inhibits synaptic activity in the lateral perforant pathway (IC 50 values are 130 and 1859 μ M in the lateral and medial perforant pathways respectively). Conformationally restrained analog of L-AP4 (Cat No. 0103 ).
[storage]

Store at -20°C
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