Identification | Back Directory | [Name]
(+/-)-1-AMINO-TRANS-3-PHOSPHONO-CYCLOPEN TANE CARBO | [CAS]
103439-17-4 | [Synonyms]
Z-Cyclopentyl-AP4 (+/-)-1-AMINO-TRANS-3-PHOSPHONO-CYCLOPEN TANE CARBO (+/-)-1-AMINO-TRANS-3-PHOSPHONO-CYCLOPEN TANE CARBO Z-Cyclopentyl-AP-4,ZCyclopentylAP4,Z Cyclopentyl AP4 cis-(±)-1-Amino-3-phosphonocyclopentanecarboxylicacid Cyclopentanecarboxylic acid, 1-amino-3-phosphono-, (1R,3S)-rel- | [Molecular Formula]
C6H12NO5P | [MOL File]
103439-17-4.mol | [Molecular Weight]
209.14 |
Hazard Information | Back Directory | [Uses]
Z-Cyclopentyl-AP4 is a Group III mGluR (mGluR-4,6) agonist. | [Biological Activity]
Group III mGlu receptor agonist that exhibits higher potency at mGlu 4 than mGlu 8 (EC 50 values are 49 and 124 μ M respectively) with no activity at mGlu 7 . Selectively inhibits synaptic activity in the lateral perforant pathway (IC 50 values are 130 and 1859 μ M in the lateral and medial perforant pathways respectively). Conformationally restrained analog of L-AP4 (Cat No. 0103 ). | [storage]
Store at -20°C |
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