| Identification | Back Directory | [Name]
Phenol, 3-chloro-4-(4H-3,4,7-triazadibenz[cd,f]azulen-6-yl)- | [CAS]
1036241-36-7 | [Synonyms]
JAK-2/3-IN-1
ZSQMMRNKHIUXPH-UHFFFAOYSA-N
Phenol, 3-chloro-4-(4H-3,4,7-triazadibenz[cd,f]azulen-6-yl)- | [Molecular Formula]
C20H12ClN3O | [MOL File]
1036241-36-7.mol | [Molecular Weight]
345.782 |
| Hazard Information | Back Directory | [Uses]
JAK-2/3-IN-1 is a potent JAK-2 and JAK-3 inhibitor extracted from patent US8163732B2, compound 46, has Kis of <250 nM for both isoforms[1]. | [IC 50]
JAK2: <250 nM (Ki); JAK3: <250 nM (Ki) | [References]
[1] Youssef Bennani, et al. Tricyclic heteroaryl compounds useful as inhibitors of Janus kinase. US8163732B2. |
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