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103787-97-9

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103787-97-9 Structure

103787-97-9 Structure
IdentificationBack Directory
[Name]

BM-131246
[CAS]

103787-97-9
[Synonyms]

BM-131246
5-{4-[2-(5-methyl-2-phenyl-4-oxazolyl)ethoxy]benzyl}-2,4-thiazolidinedione
2,4-Thiazolidinedione, 5-[[4-[2-(5-methyl-2-phenyl-4-oxazolyl)ethoxy]phenyl]methyl]-
[Molecular Formula]

C22H20N2O4S
[MDL Number]

MFCD00911050
[MOL File]

103787-97-9.mol
[Molecular Weight]

408.47
Chemical PropertiesBack Directory
[density ]

1.299±0.06 g/cm3(Predicted)
[storage temp. ]

Store at -20°C
[solubility ]

Soluble in DMSO
[pka]

6.35±0.50(Predicted)
Hazard InformationBack Directory
[Uses]

BM-131246 is an oral antidiabetic agent.
[in vivo]

BM-131246 is absorbed quickly and attains approximately proportional increase of the plasma levels in ob/ob mice. After repeated oral doses the terminal half-lives is about 4 h for BM-131246[1].

[storage]

Store at -20°C
[References]

[1] Heitzmann T, et al. Dose proportionality studies of novel thiazolidinedione derivatives as potent antidiabetic agents in mice. Arzneimittelforschung. 1995 Dec;45(12):1284-8. PMID:8595085
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