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103795-84-2

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103795-84-2 Structure

103795-84-2 Structure
IdentificationBack Directory
[Name]

Hydrocortisone IMpurity I
[CAS]

103795-84-2
[Synonyms]

Hydrocortisone IMpurity I
14α-Hydroxyhydrocortisone
Hydrocortisone EP Impurity I
Hydrocortisone impurity I (EP)
11β,14,17,21-tetrahydroxypregn-4-ene-3,20-dione
Hydrocortisone Impurity 9（Hydrocortisone EP Impurity I）
Pregn-4-ene-3,20-dione, 11,14,17,21-tetrahydroxy-, (11β)-
[Molecular Formula]

C21H30O6
[MOL File]

103795-84-2.mol
[Molecular Weight]

378.46
Chemical PropertiesBack Directory
[Melting point ]

241-242 °C
[Boiling point ]

602.3±55.0 °C(Predicted)
[density ]

1.35±0.1 g/cm3(Predicted)
[pka]

12.10±0.70(Predicted)
Safety DataBack Directory
[Symbol(GHS) ]

Exclamation Mark (GHS07)
GHS07
[Signal word ]

Warning
[Hazard statements ]

H315-H319
[Precautionary statements ]

P264-P280-P302+P352-P337+P313-P305+P351+P338-P362+P364-P332+P313
Hazard InformationBack Directory
[Uses]

14α-Hydroxycortisol (Hydrocortisone EP Impurity I) is an impurity of Hydrocortisone (H714615), a topical corticosteroid (1), but more specifically a glucocorticoid, produced by the zona fasciculata of the adrenal gland (2). Cortisol is released in response to stress and a low level of blood glucocorticoids. Its primary functions are to increase blood sugar through gluconeogenesis; suppress the immune system; and aid in fat, protein and carbohydrate metabolism.
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