| Identification | Back Directory | [Name]
gemcitabine | [CAS]
103882-84-4 | [Synonyms]
C056507
2',2'-Dfdc
2'-Deoxy-2'-difluorocytidine
Gemcitabine, (alpha-D-threo-pentofuranosyl)-isomer
2'-Deoxy-2',2''-difluorocytidine-5'-o-monophosphate
4-?amino-?1-?(2-?deoxy-?2,?2-?difluoro-?D-?erythro-?pentofuranosyl)?-2(1H)?-?Pyrimidinone | [Molecular Formula]
C9H11F2N3O4 | [MOL File]
103882-84-4.mol | [Molecular Weight]
263.2 |
| Hazard Information | Back Directory | [Uses]
Gemcitabine is a nucleoside analog with anti-cancer properties. An inhibitor of DNA synthesis active on solid tumors. | [Definition]
ChEBI: Gemcitabine is a 2'-deoxycytidine having geminal fluoro substituents in the 2'-position. An inhibitor of ribonucleotide reductase, gemcitabine is used in the treatment of various carcinomas, particularly non-small cell lung cancer, pancreatic cancer, bladder cancer and breast cancer. It has a role as a photosensitizing agent, a DNA synthesis inhibitor, a prodrug, an EC 1.17.4.1 (ribonucleoside-diphosphate reductase) inhibitor, an environmental contaminant, a xenobiotic, a radiosensitizing agent, an antineoplastic agent, an antimetabolite, an antiviral drug and an immunosuppressive agent. It is an organofluorine compound and a pyrimidine 2'-deoxyribonucleoside. |
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| Company Name: |
Energy Chemical
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| Telephone: |
021-58432009 400-005-6266 |
| Website: |
http://www.energy-chemical.com |
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