| Identification | Back Directory | [Name]
CP 67804 | [CAS]
103978-08-1 | [Synonyms]
804
CP 67804
CCRIS 8213
CP67804,CP 67804
3-Quinolinecarboxylic acid, 1-ethyl-6,8-difluoro-1,4-dihydro-7-(4-hydroxyphenyl)-4-oxo- | [Molecular Formula]
C18H13F2NO4 | [MDL Number]
MFCD00907884 | [MOL File]
103978-08-1.mol | [Molecular Weight]
345.3 |
| Hazard Information | Back Directory | [Uses]
CP-67804 is a quinolone derivative, is a topoisomerase II-targeted agent. CP-67804 effectively enhances DNA cleavage mediated by eukaryotic topoisomerase II. CP-67804 has potential as an antineoplastic agent[1]. | [IC 50]
Topoisomerase II | [References]
[1] Robinson MJ, et al. Effects of quinolone derivatives on eukaryotic topoisomerase II. A novel mechanism for enhancement of enzyme-mediated DNA cleavage. J Biol Chem. 1991;266(22):14585-14592. PMID:1650363 |
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