| Identification | Back Directory | [Name]
Abz-Val-Ala-Asp-Nva-Arg-Asp-Arg-Gln-EDDnp | [CAS]
1042405-14-0 | [Synonyms]
Abz-Val-Ala-Asp-Nva-Arg-Asp-Arg-Gln-EDDnp
L-Glutamamide, N-(2-aminobenzoyl)-L-valyl-L-alanyl-L-α-aspartyl-L-norvalyl-L-arginyl-L-α-aspartyl-L-arginyl-N1-[2-[(2,4-dinitrophenyl)amino]ethyl]- | [Molecular Formula]
C53H80N20O18 | [MDL Number]
MFCD34549090 | [MOL File]
1042405-14-0.mol | [Molecular Weight]
1285.33 |
| Chemical Properties | Back Directory | [density ]
1.54±0.1 g/cm3(Predicted) | [form ]
Solid | [pka]
4.19±0.10(Predicted) | [color ]
White to yellow | [Sequence]
{Abz}-Val-Ala-Asp-{Nva}-Arg-Asp-Arg-Gln-{EDDnp} |
| Hazard Information | Back Directory | [Uses]
Abz-Val-Ala-Asp-Nva-Arg-Asp-Arg-Gln-EDDnp is a fluorescence-quenched peptide substrate for human proteinase 3 (kcat/Km = 1,570 mM-1s-1), and can be used for detection of proteinase 3 (PR3) activity[1][2]. | [References]
[1] Yu J, et al. Cathepsin C from extracellular histone-induced M1 alveolar macrophages promotes NETosis during lung ischemia-reperfusion injury. Redox Biol. 2024 Jun 6;74:103231. DOI:10.1016/j.redox.2024.103231
[2] Korkmaz B, et al. Measurement of neutrophil elastase, proteinase 3, and cathepsin G activities using intramolecularly quenched fluorogenic substrates. Methods Mol Biol. 2012;844:125-38. DOI:10.1007/978-1-61779-527-5_9 |
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| Company Name: |
Enzo Biochem Inc
|
| Tel: |
Enzo Biochem Inc. 13797054060 |
| Website: |
www.enzo.com |
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