| Identification | Back Directory | [Name]
(+/-)-7,8-Dihydroxy-3-allyl-1-phenyl-2,3,4,5-tetrahydro-1H-3-benzazepine hydrobromide | [CAS]
104422-04-0 | [Synonyms]
sk&f77434
SKF 77434 HYDROBROMIDE
(+/-)-SKF-77434 HYDROBROMIDE
(+/-)-N-ALLYL-SKF-38393 HYDROBROMIDE
(+/-)-SKF-38393, N-ALLYL-, HYDROBROMIDE
(+)-SKF-38393, N-ALLYL-, HYDROBROMIDE D1 DOPAMINE AGONIST
N-allyl-1-phenyl-2,3,4,5-tetrahydro-3-benzazepine-7,8-diol
2,3,4,5-Tetrahydro-1-phenyl-3-(2-propenyl)-1H-3-benzazepine-7,8-diol
1H-3-Benzazepine-7,8-diol, 2,3,4,5-tetrahydro-1-phenyl-3-(2-propen-1-yl)-
2,3,4,5-TETRAHYDRO-1-PHENYL-3-(2-PROPENYL)-1H-3-BENZAZEPINE-7,8-DIOL HYDROBROMIDE
(+/-)-7,8-Dihydroxy-3-allyl-1-phenyl-2,3,4,5-tetrahydro-1H-3-benzazepine hydrobromide | [Molecular Formula]
C19H21NO2 | [MDL Number]
MFCD00243077 | [MOL File]
104422-04-0.mol | [Molecular Weight]
295.38 |
| Chemical Properties | Back Directory | [Boiling point ]
470.406±45.00 °C(Press: 760.00 Torr)(predicted) | [density ]
1.157±0.06 g/cm3(Temp: 25 °C; Press: 760 Torr)(predicted) | [storage temp. ]
2-8°C | [solubility ]
ethanol: 3.2 mg/mL | [form ]
solid | [pka]
10.186±0.40(predicted) | [color ]
white or off-white |
| Hazard Information | Back Directory | [Uses]
N-Allyl-(+/-)-SKF-38393 hydrobromide is a selective dopamine D1-like receptor partial agonist. | [Definition]
ChEBI: A benzazepine that is 2,3,4,5-tetrahydro-3-benzazepine bearing a phenyl substituent at position 1, an allyl substituent at position 3 and two hydroxy substituents at positions 7 and 8. Selective dopamine D1-like receptor partial agonist (IC50 values are 19
7 and 2425 nM for binding to D1-like and D2-like receptors respectively). Centrally active following systemic administration in vivo. | [Biological Activity]
Selective dopamine D 1 -like receptor partial agonist (IC 50 values are 19.7 and 2425 nM for binding to D 1 -like and D 2 -like receptors respectively). Centrally active following systemic administration in vivo . |
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