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104494-35-1

104494-35-1 Structure

104494-35-1 Structure
IdentificationBack Directory
[Name]

1,2-Benzenediol, 5-[3-(2,4-dihydroxyphenyl)propyl]-3,4-bis(3-methyl-2-buten-1-yl)-
[CAS]

104494-35-1
[Synonyms]

Kazinol F
1,2-Benzenediol, 5-[3-(2,4-dihydroxyphenyl)propyl]-3,4-bis(3-methyl-2-buten-1-yl)-
[Molecular Formula]

C25H32O4
[MOL File]

104494-35-1.mol
[Molecular Weight]

396.52
Chemical PropertiesBack Directory
[Melting point ]

108-109 °C
[Boiling point ]

590.0±45.0 °C(Predicted)
[density ]

1.150±0.06 g/cm3(Predicted)
[pka]

9.94±0.20(Predicted)
Hazard InformationBack Directory
[Description]

Kazinol F is greatly effective for skin brightening.
[Uses]

Kazinol F is a polyphenol from Broussonetia papyrifera. Kazinol F also is an effective Mpro inhibitor. Kazinol F has interaction with both the catalytic residues (His41 and Cys145) of Mpro and exhibits good binding affinity. Kazinol F can be used for the research of COVID-19[1].
[References]

[1] Ghosh, Rajesh et al. Identification of polyphenols from Broussonetia papyrifera as SARS CoV-2 main protease inhibitors using in silico docking and molecular dynamics simulation approaches. J Biomol Struct Dyn. vol. 39,17 (2021): 6747-6760. DOI:10.1080/07391102.2020.1802347
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