| Identification | Back Directory | [Name]
7-METHYLGUANOSINE 5'-TRIPHOSPHATE SODIUM SALT | [CAS]
104809-18-9 | [Synonyms]
m7GTP
7-Methylguanosine 5′-triphosphate
7-METHYLGUANOSINE 5'-TRIPHOSPHATE SODIUM SALT
7-methylguanosine 5'-triphosphate*sodium approx.
7-METHYLGUANOSINE 5'-TRIPHOSPHATE*SODIUM APPROX. 90
7-Methylguanosine 5'-triphosphate sodium salt >=85% (HPLC) | [Molecular Formula]
C11H18N4NaO14P3 | [MDL Number]
MFCD00063376 | [MOL File]
104809-18-9.mol | [Molecular Weight]
546.19 |
| Chemical Properties | Back Directory | [storage temp. ]
-20°C | [solubility ]
water: 50 mg/mL, clear, colorless to faint yellow or tan | [form ]
powder | [biological source]
natural (inorganic) | [InChIKey]
FSMRTZAMTMQMEF-OCMBMSOASA-M | [SMILES]
[Na+].C[n+]1cn([C@@H]2O[C@H](COP(O)(=O)OP(O)(=O)OP(O)([O-])=O)[C@@H](O)[C@H]2O)c3N=C(N)NC([O-])c13 |
| Safety Data | Back Directory | [Hazard Codes ]
Xn | [Risk Statements ]
22 | [WGK Germany ]
3 | [Storage Class]
11 - Combustible Solids | [Hazard Classifications]
Acute Tox. 4 Oral |
| Hazard Information | Back Directory | [Uses]
7-Methylguanosine 5′-triphosphate (m7GTP) is use to study the structures and mechanisms of eukaryotic cellular mRNA caps in the context of mRNA involvement in protein synthesis. m7GTP may be used to create affinity media for capture and purification of molecules such as eukaryotic initiation factor eIF4E. | [General Description]
7-Methylguanosine 5′-triphosphate is a mRNA cap structural analog. | [Biochem/physiol Actions]
7-Methylguanosine 5′-triphosphate (m7GTP) inhibits in vitro protein synthesis by binding to translation initiation complexes. m7GTP is useful to study the structures and mechanisms of eukaryotic cellular mRNA caps in the context of mRNA involvement in protein synthesis. m7GTP has a high affinity for eukaryotic initiation factor eIF4E and may be used to create affinity media for their capture and purification. |
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