1048973-47-2

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1048973-47-2 Structure

Identification	Back Directory
[Name] MDA 19
[CAS] 1048973-47-2
[Synonyms] MDA 19 MDA19; MDA-19 N'-(1-Hexyl-2-oxoindolin-3-ylidene)benzohydrazide (Z)-N'-(1-hexyl-2-oxoindolin-3-ylidene)benzohydrazide N-[(Z)-(1-Hexyl-2-oxo-indolin-3-ylidene)aMino]benzaMide N'-[(3Z)-1-Hexyl-2-oxo-1,2-dihydro-3H-indol-3-ylidene]benzohydrazide Benzoic acid (2Z)-2-(1-hexyl-1,2-dihydro-2-oxo-3H-indol-3-ylidene)hydrazide MDA 19 (Z)-N'-(1-hexyl-2-oxoindolin-3-ylidene)benzohydrazide
[EINECS(EC#)] 200-258-5
[Molecular Formula] C21H23N3O2
[MDL Number] MFCD23135890
[MOL File] 1048973-47-2.mol
[Molecular Weight] 349.43

Chemical Properties	Back Directory
[density ] 1.16±0.1 g/cm3 (20 ºC 760 Torr)
[storage temp. ] Store at -20°C
[solubility ] DMF: 20 mg/ml; DMSO: 10 mg/ml; Ethanol: 3 mg/ml; Methanol: 1 mg/ml
[form ] A crystalline solid
[pka] 10.45±0.20(Predicted)
[color ] Light yellow to yellow

Hazard Information	Back Directory
[Uses] MDA 19 is a selective agonist of the human peripheral cannabinoid (CB2) receptor. A cell-based functional assay showed MDA is an inverse agonist of the CB2 receptor in rat. Acts as an inverse agonist at the rat CB2 receptor. Reported Ki values are 16.3 and 1130 nM for human CB2 and CB1 receptor respectively. MDA19 was effective in attenuating tactile allodynia in neuropathic rats. MDA19 thus has potential for alleviating neuropathic pain without producing adverse effects in the central nervous system.Synthetic Cannabinoids
[storage] Store at -20°C

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