ChemicalBook--->CAS DataBase List--->104944-18-5

104944-18-5

104944-18-5 Structure

104944-18-5 Structure
IdentificationBack Directory
[Name]

H-D-Val-OtBu.HCl
[CAS]

104944-18-5
[Synonyms]

H-D-Val-OtBu
D-Val-OtBu·HCl
H-D-Val-OtBu•
tert-Butyl L-valinate HCl
H-D-Val-OtBu.HCl USP/EP/BP
D-Valine tert-butyl ester, HCl
H-D-VAL-OTBU HCL CAS:104944-18-5
D-VALINE TERT-BUTYL ESTER HYDROCHLORIDE
D-Valine 1,1-dimethylethyl ester hydrochloride
D-Valine,1,1-diMethylethyl ester, hydrochloride (1:1)
(R)-tert-butyl 2-amino-3-methylbutanoate hydrochloride
tert-butyl (2R)-2-amino-3-methylbutanoate hydrochloride
[Molecular Formula]

C9H20ClNO2
[MDL Number]

MFCD00237308
[MOL File]

104944-18-5.mol
[Molecular Weight]

209.714
Questions And AnswerBack Directory
[Synthesis]

D-valine was used as a starting material and reacted with di-tert-butyl dicarbonate under Et 3 N/MeOH conditions for Boc protection to prepare the target compound, H-D-Val-OtBu.HCl. The reaction formula for the preparation of H-D-Val-OtBu.HCl is shown in the figure below:

Synthesis of 104944-18-5

Chemical PropertiesBack Directory
[Melting point ]

144-146℃
[storage temp. ]

Inert atmosphere,Store in freezer, under -20°C
[solubility ]

Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc.
[form ]

Powder
[color ]

White to off-white
Safety DataBack Directory
[Symbol(GHS) ]

Exclamation Mark (GHS07)
GHS07
[Signal word ]

Warning
[Hazard statements ]

H315-H335-H319
[Precautionary statements ]

P264-P280-P305+P351+P338-P337+P313P-P264-P280-P302+P352-P321-P332+P313-P362
Hazard InformationBack Directory
[Chemical Properties]

White powder
[Uses]

D-Valine tert-butyl ester hydrochloride is a protected form of D-Valine (V094220). D-Valine (an isomer of the essential amino acid L-Valine [V094205])exhibited inhibitory effects on fibroblasts that contaminated mammalian kidney cultures, allowing for selective growth epithelial cells. D-Valine is also known for its presence in the structure of Actinomycin D, an antitumour drug. D-Valine is naturally synthesized by Streptomyces antibioticus.
Spectrum DetailBack Directory
[Spectrum Detail]

H-D-Val-OtBu.HCl(104944-18-5)1HNMR
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