| Identification | Back Directory | [Name]
Adenosine phosphonobutyric, 2'(3'), 5'-diposphate | [CAS]
1050202-63-5 | [Synonyms]
Adenosine phosphonobutyric, 2'(3'), 5'-diposphate | [Molecular Formula]
C14H22N5O16P3 | [MOL File]
1050202-63-5.mol | [Molecular Weight]
609.27 |
| Chemical Properties | Back Directory | [Boiling point ]
1147.333±75.00 °C(Press: 760.00 Torr)(predicted) | [density ]
2.378±0.14 g/cm3(Temp: 25 °C; Press: 760 Torr)(predicted) | [pka]
1.835±0.10(predicted) |
| Hazard Information | Back Directory | [Uses]
Adenosine phosphonobutyric, 2'(3'), 5'-diposphate (APBADP) is a potent Bacillus subtilis and human adenylosuccinate lyase (ASL) inhibitor. Adenosine phosphonobutyric, 2'(3'), 5'-diposphate also is a competitive succinylaminoimidazole carboxamide ribotide (SAICAR) inhibitor[1]. | [References]
[1] Sivendran S, et al. Effect of a new non-cleavable substrate analog on wild-type and serine mutants in the signature sequence of adenylosuccinate lyase of Bacillus subtilis and Homo sapiens. Protein Sci. 2008 Jul;17(7):1162-74. DOI:10.1110/ps.034777.108 |
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