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105336-14-9

105336-14-9 Structure

105336-14-9 Structure
IdentificationBack Directory
[Name]

Azumolene Sodium Salt
[CAS]

105336-14-9
[Synonyms]

EU 4093
Azumolene Sodium Salt
1-[[[5-(4-Bromophenyl)-2-oxazolyl]methylene]amino]-2,4-imidazolidinedione Sodium Sal
1-[[[5-(4-Bromophenyl)-2-oxazolyl]methylene]amino]-2,4-imidazolidinedione Sodium Salt
[Molecular Formula]

C13H8BrN4NaO3
[MDL Number]

MFCD09839973
[MOL File]

105336-14-9.mol
[Molecular Weight]

371.125
Chemical PropertiesBack Directory
[Appearance]

Off-White to Pale Yellow Solid
[Melting point ]

>240°C (dec.)
[storage temp. ]

Hygroscopic, Refrigerator, Under Inert Atmosphere
[solubility ]

Acetonitrile (Slightly), DMSO (Slightly), Water (Slightly)
[form ]

Solid
[color ]

Off-White to Pale Yellow
Hazard InformationBack Directory
[Chemical Properties]

Off-White to Pale Yellow Solid
[Uses]

Skeletal muscle relaxant
[Description]

Azumolene is a muscle relaxant that inhibits the release of calcium from skeletal muscle sarcoplasmic reticulum. It inhibits a component of store-operated calcium entry (SOCE) that is coupled to the skeletal muscle ryanodine receptor, with 20 μM azumolene causing a 70% reduction in SOCE in myotubes. Azumolene has utility in countering muscle dysfunction associated with malignant hyperthermia.
[Definition]

ChEBI: Azumolene sodium is the anhydrous sodium salt of azumolene. It contains an azumolene(1-).
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