| Identification | Back Directory | [Name]
BMS 695735 | [CAS]
1054315-48-8 | [Synonyms]
BDBM27888
DNC008930
BMS 695735
CHEMBL459729
BMS 695735
(BMS695735)
VWELCPLMPPEKOL-UHFFFAOYSA-N
2(1H)-Pyridinone, 4-[[2-(4-chloro-1H-pyrazol-1-yl)ethyl]amino]-3-[5-[1-(3-fluoropropyl)-4-piperidinyl]-7-methyl-1H-benzimidazol-2-yl]- | [Molecular Formula]
C26H31ClFN7O | [MDL Number]
MFCD25977743 | [MOL File]
1054315-48-8.mol | [Molecular Weight]
512.02 |
| Hazard Information | Back Directory | [Uses]
BMS 695735 (compound 10) is an inhibitor of IGF-1R with an IC50 value of 0.034 μM. BMS 695735 has anti-tumor activity[1]. | [References]
[1] Discovery and Evaluation of 4-(2-(4-chloro-1H-pyrazol-1-yl)ethylamino)-3-(6-(1-(3-fluoropropyl)piperidin-4-yl)-4-methyl-1H-benzo[d]imidazol-2-yl)pyridin-2(1H)-one (BMS-695735), an Orally Efficacious Inhibitor of Insulin-like Growth Factor-1 Receptor Kinase with Broad Spectrum in Vivo Antitumor Activity
J. Med. Chem., 2008, 51 (19), pp 5897-5900 DOI:10.1021/jm800832q |
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| Company Name: |
BOC Sciences
|
| Tel: |
1-631-485-4226; 16314854226 |
| Website: |
https://www.bocsci.com |
| Company Name: |
BOC Sciences
|
| Tel: |
16314854226 |
| Website: |
www.bocsci.com |
|