| Identification | Back Directory | [Name]
LP117 | [CAS]
1056468-55-3 | [Synonyms]
LP117
LP117,LP-117
LP117 >=98% (HPLC)
Hexanoic acid, 2-[[4-chloro-6-(6-quinolinylamino)-2-pyrimidinyl]thio]-, ethyl ester | [Molecular Formula]
C21H23ClN4O2S | [MDL Number]
MFCD30534128 | [MOL File]
1056468-55-3.mol | [Molecular Weight]
430.95 |
| Chemical Properties | Back Directory | [Boiling point ]
577.1±50.0 °C(Predicted) | [density ]
1.31±0.1 g/cm3(Predicted) | [storage temp. ]
Store at -20°C | [solubility ]
Soluble in DMSO | [pka]
4.79±0.10(Predicted) |
| Hazard Information | Back Directory | [Uses]
LP117 is a novel and potent inhibitor of 5-Lipoxygenase (5-LO) product synthesis with an IC50 of 1.1 μM. | [IC 50]
5-LO: 1.1 μM (IC50) | [References]
[1] Werz O, et al. Novel and potent inhibitors of 5-lipoxygenase product synthesis based on the structure of pirinixic acid. J Med Chem. 2008 Sep 11;51(17):5449-53. DOI:10.1021/jm800588x |
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| Company Name: |
Energy Chemical
|
| Tel: |
021-58432009 400-005-6266 |
| Website: |
http://www.energy-chemical.com |
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