| Identification | Back Directory | [Name]
PYRIMIDIFEN | [CAS]
105779-78-0 | [Synonyms]
SU-9118
-4-amine
MITECLEAN
Pyrimedifen
PYRIMIDIFEN
PYRIMIDIFEN STANDARD
Pyrimidifen solution
pyrimidifen (bsi,iso)
Pyrimidifen Solution, 100ppm
Pyrimidifen@100 μg/mL in Methanol
Pyrimidifen@1000 μg/mL in Acetone
5-chloro-n-(2-(4-(2-ethoxyethyl)-2,3-dimethylphenoxy)ethyl)-6-ethylpyrimidin
4-pyrimidinamine,5-chloro-n-(2-(4-(2-ethoxyethyl)-2,3-dimethylphenoxy)ethyl)-6
5-Chloro-N-[2-[4-(2-ethoxyethyl)-2,3-dimethylphenoxy]ethyl]-6-ethyl-4-pyrimidinamine
5-Chloro-N-{2-[4-(2-ethoxyethyl)-2,3-dimethylphenoxy]ethyl}-6-ethylpyrimidin-4-amine
4-Pyrimidinamine, 5-chloro-N-[2-[4-(2-ethoxyethyl)-2,3-dimethylphenoxy]ethyl]-6-ethyl- | [Molecular Formula]
C20H28ClN3O2 | [MDL Number]
MFCD01631162 | [MOL File]
105779-78-0.mol | [Molecular Weight]
377.91 |
| Chemical Properties | Back Directory | [Melting point ]
157-161℃ | [Boiling point ]
535.6±50.0 °C(Predicted) | [density ]
1.45 | [storage temp. ]
0-6°C | [form ]
neat | [pka]
4.09±0.10(Predicted) | [BRN ]
11644658 | [Major Application]
agriculture
environmental | [InChI]
1S/C20H28ClN3O2/c1-5-17-19(21)20(24-13-23-17)22-10-12-26-18-8-7-16(9-11-25-6-2)14(3)15(18)4/h7-8,13H,5-6,9-12H2,1-4H3,(H,22,23,24) | [InChIKey]
ITKAIUGKVKDENI-UHFFFAOYSA-N | [SMILES]
CCOCCc1ccc(OCCNc2ncnc(CC)c2Cl)c(C)c1C |
| Safety Data | Back Directory | [Hazard Codes ]
Xn,N | [Risk Statements ]
22-50/53 | [Safety Statements ]
60-61 | [RIDADR ]
UN2811 - class 6.1 - PG 3 - EHS - Toxic solids, organic, n.o.s., HI: all | [WGK Germany ]
3 | [Storage Class]
6.1C - Combustible acute toxic Cat.3
toxic compounds or compounds which causing chronic effects | [Hazard Classifications]
Acute Tox. 3 Oral
Aquatic Acute 1
Aquatic Chronic 1 |
| Hazard Information | Back Directory | [Uses]
Pyrimidifen is used as pesticide. | [Definition]
ChEBI: Pyrimidifen is a pyrimidinamine insecticide, a pyrimidinamine acaricide and an aminopyrimidine. It has a role as a mitochondrial NADH:ubiquinone reductase inhibitor. | [Synthesis]
First, the key pyrimidine intermediate, 4,5-dichloro-6-ethylpyrimidine, was prepared. Simultaneously, an intermediate containing a phenoxyethyl side chain was prepared by reacting 4-(2-ethoxyethyl)-2,3-dimethylphenol with 1,2-dihaloethane or 2-haloethylamine. Subsequently, under basic conditions (e.g., using triethylamine or potassium carbonate) in an organic solvent, this pyrimidine intermediate underwent a nucleophilic substitution reaction with a side-chain amine intermediate to form an N-substituted pyrimidine-4-amine skeleton. Finally, by selective chlorination to ensure or introduce a chlorine atom at the 5-position, the Pyrimidifen was obtained. |
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| Company Name: |
Energy Chemical
|
| Tel: |
021-58432009 400-005-6266 |
| Website: |
http://www.energy-chemical.com |
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