| Identification | Back Directory | [Name]
Benzeneacetamide, N-[2-[(1R)-2-amino-1-methylethyl]-1,2-dihydro-6-methyl-1-oxo-5-isoquinolinyl]-3-fluoro-4-(trifluoromethyl)- | [CAS]
1058709-63-9 | [Synonyms]
P2X7-IN-2
Benzeneacetamide, N-[2-[(1R)-2-amino-1-methylethyl]-1,2-dihydro-6-methyl-1-oxo-5-isoquinolinyl]-3-fluoro-4-(trifluoromethyl)- | [Molecular Formula]
C22H21F4N3O2 | [MOL File]
1058709-63-9.mol | [Molecular Weight]
435.41 |
| Hazard Information | Back Directory | [Uses]
P2X7-IN-2 (compound 58) is a P2X7 receptor inhibitor. P2X7-IN-2 inhibits IL-Iβ release with an IC50 value of 0.01 nM. P2X7-IN-2 can be used for the research of autoimmunity, inflammation and cardiovascular disease[1]. | [References]
[1] Kelly, Michael G, et al. Preparation of isoquinolonecarboxamides as P2X7 purinoceptor modulators and uses thereof. WO2008112205 A1. 2008. |
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