| Identification | Back Directory | [Name]
5-broMo-4-chloropyridine-2-carboxylic acid | [CAS]
1060802-25-6 | [Synonyms]
5-broMo-4-chloropicolinic acid
5-BroMo-4-chloro-2-pyridinecarboxylic acid
5-broMo-4-chloropyridine-2-carboxylic acid
2-Pyridinecarboxylic acid, 5-bromo-4-chloro- | [Molecular Formula]
C6H3BrClNO2 | [MDL Number]
MFCD13189053 | [MOL File]
1060802-25-6.mol | [Molecular Weight]
236.45 |
| Chemical Properties | Back Directory | [Boiling point ]
341.5±42.0 °C(Predicted) | [density ]
1.917±0.06 g/cm3(Predicted) | [storage temp. ]
Inert atmosphere,2-8°C | [pka]
3.04±0.10(Predicted) | [Appearance]
White to off-white Solid |
| Hazard Information | Back Directory | [Synthesis]
e) An aqueous solution of potassium permanganate (174 mg, 1.1 mmol) was slowly added dropwise to a solution of (5-bromo-4-chloropyridin-2-yl) methanol (187 mg, 0.846 mmol) dissolved in 10% sodium carbonate (1 mL). After 2 hours of reaction, the mixture was filtered through diatomaceous earth and the pH of the filtrate was subsequently adjusted to about 4. The precipitate precipitated was collected by filtration. Finally, it was dried by azeotropic drying with toluene to give the white powdery product 5-bromo-4-chloro-pyridine-2-carboxylic acid (135 mg, 68% yield): lcms (ES) m/z = 237 (M + H)+. | [References]
[1] Patent: WO2008/121786, 2008, A1. Location in patent: Page/Page column 57 |
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SynAsst Chemical.
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