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106396-24-1

106396-24-1 Structure

106396-24-1 Structure
IdentificationBack Directory
[Name]

estatin B
[CAS]

106396-24-1
[Synonyms]

estatin B
3-[[[2-[[4-[(Aminoiminomethyl)amino]butyl]amino]-1-[(4-hydroxyphenyl)methyl]-2-oxoethyl]amino]carbonyl]-2-oxiranecarboxylic acid
Oxiranecarboxylic acid, 3-[[[2-[[4-[(aminoiminomethyl)amino]butyl]amino]-1-[(4-hydroxyphenyl)methyl]-2-oxoethyl]amino]carbonyl]- (9CI)
[Molecular Formula]

C18H25N5O6
[MDL Number]

MFCD01747978
[MOL File]

106396-24-1.mol
[Molecular Weight]

407.42
Chemical PropertiesBack Directory
[density ]

1.53±0.1 g/cm3(Predicted)
[pka]

3.15±0.40(Predicted)
Hazard InformationBack Directory
[Uses]

Estatin B is a thiol protease inhibitor found by the Thermophilic Bacterium M4323, which is specific to thiol proteases such as papain, fig protease, and bromelain. Estatin B inhibits the production of IgE antibodies but not IgG in mice[1].
[References]

[1] S Yaginuma, et al. Isolation and characterization of new thiol protease inhibitors estatins A and B. J Antibiot (Tokyo). 1989 Sep;42(9):1362-9. DOI:10.7164/antibiotics.42.1362
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