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106500-25-8

106500-25-8 Structure

106500-25-8 Structure
IdentificationBack Directory
[Name]

AZADIRACHTIN B(SH)
[CAS]

106500-25-8
[Synonyms]

AZADIRACHTIN B(SH)
Deacetylazadirachtinol
7H,8H-Furo[3',4':4,4a]naphtho[1,8-bc]furan-5,10a(1H)-dicarboxylic acid, octahydro-3,8-dihydroxy-4-methyl-10-[[(2E)-2-methyl-1-oxo-2-buten-1-yl]oxy]-4-[(1aR,2S,3aS,6aS,7S,7aS)-3a,6a,7,7a-tetrahydro-6a-hydroxy-7a-methyl-2,7-methanofuro[2,3-b]oxireno[e]oxepin-1a(2H)-yl]-, 5,10a-dimethyl ester, (2aR,3S,...
[Molecular Formula]

C33H42O14
[MDL Number]

MFCD00083241
[MOL File]

106500-25-8.mol
[Molecular Weight]

662.68
Chemical PropertiesBack Directory
[Boiling point ]

780.5±60.0 °C(Predicted)
[density ]

1.49±0.1 g/cm3(Predicted)
[storage temp. ]

Store at -20°C
[solubility ]

Chloroform: slightly soluble; DMSO: slightly soluble; Methanol: slightly soluble
[form ]

A solid
[pka]

11.99±0.60(Predicted)
[color ]

White to off-white
[Stability:]

Light Sensitive
Hazard InformationBack Directory
[Uses]

Azadirachtin B is a drug analog of azadirachtin which was investigated in agrochemical studies of bioregulators for the antifeedant mode of action of parent molecule against Lepidoptera and locusts.
[Biological Activity]

Azadirachtin B is a limonoid isolated from the seed kernel of Azadirachta indica. It increases alkaline phosphatase (ALP) activity and stimulates osteoblast differentiation.
[in vivo]

On evaluation of Azadirachtin B (compound 21; oral administration) for its anti-tumor-initiating activity on the two-stage carcinogenesis of mouse skin tumor induced by peroxynitrite (ONOO-; PN) as an initiator and TPA as a promoter, this exhibited marked inhibitory activity.

[target]

Plutella xylostella
Alkaline phosphatase (ALP)
Epstein-Barr virus early antigen (EBV-EA)

[storage]

Store at -20°C
Spectrum DetailBack Directory
[Spectrum Detail]

AZADIRACHTIN B(SH)(106500-25-8)1HNMR
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