| Identification | Back Directory | [Name]
(3S 5R 8AS)-(+)-HEXAHYDRO-3-PHENYL-5H-O& | [CAS]
106565-71-3 | [Synonyms]
XL 518 intermediate
Cobimetinib Impurity 1
(3S 5R 8AS)-(+)-HEXAHYDRO-3-PHENYL-5H-O&
(3S 5R 8AS)-(+)-HEXAHYDRO-3-PHENYL-5H-O&
(3S,5R,8aS)-3-phenyl-3,5,6,7,8,8a-hexahydro-2H-oxazolo[2,3-f...
(3S,5R,8aS)-3-Phenylhexahydro-2H-oxazolo[3,2-a]pyridine-5-carbonitrile
5H-Oxazolo[3,2-a]pyridine-5-carbonitrile, hexahydro-3-phenyl-, (3S,5R,8aS)-
(3S,5R,8aS)-3-phenyl-3,5,6,7,8,8a-hexahydro-2H-oxazolo[2,3-f]pyridine-5-carbonitrile
[5H.oxazolo[3,2-a]piperidine-5-Carbonitrice,hexahydro-3-phenyl-[3alpha,5beta,8alpha,beta]
(+)-2-Cyano-6-phenyloxazolopiperidine, [3-S-(3α,5β,8ab)]-Hexahydro-3-phenyl-5-H-oxazolo[3,2-a]pyridine-5-carbonitrile | [EINECS(EC#)]
634-598-5 | [Molecular Formula]
C14H16N2O | [MDL Number]
MFCD08276761 | [MOL File]
106565-71-3.mol | [Molecular Weight]
228.29 |
| Chemical Properties | Back Directory | [Melting point ]
79-83 °C(lit.) | [form ]
solid | [InChI]
1S/C14H16N2O/c15-9-12-7-4-8-14-16(12)13(10-17-14)11-5-2-1-3-6-11/h1-3,5-6,12-14H,4,7-8,10H2/t12-,13-,14+/m1/s1 | [InChIKey]
GQHMNZGZXHZLEN-IUZLNWEFSA-N | [SMILES]
[H][C@]12CCC[C@H](C#N)N1[C@H](CO2)c3ccccc3 |
| Safety Data | Back Directory | [Symbol(GHS) ]
GHS07 | [Signal word ]
Warning | [Hazard statements ]
H302 | [Precautionary statements ]
P280-P305+P351+P338 | [Hazard Codes ]
Xn | [Risk Statements ]
22 | [WGK Germany ]
2 | [REACH Registrations]
Inactive | [Storage Class]
13 - Non Combustible Solids | [Hazard Classifications]
Acute Tox. 4 Oral |
| Hazard Information | Back Directory | [Uses]
(3S,5R,8aS)-(+)-Hexahydro-3-phenyl-5H-oxazolo[3,2-a]pyridine-5-carbonitrile can be used as a starting material:
- To prepare spirocyclic aminochroman derivatives as possible 5-HT1A agonists.
- In the asymmetric synthesis of aza-analogs of podophyllotoxin as potent antitumor agents.
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Energy Chemical
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Sigma-Aldrich
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https://www.sigmaaldrich.cn |
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Cck Pharmchem Co.,Ltd
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