1071966-17-0

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1071966-17-0 Structure

Chemical Properties	Back Directory
[Boiling point ] 363.5±37.0 °C(predicted)
[density ] 1.457±0.06 g/cm3(Temp: 20 °C; Press: 760 Torr)(predicted)
[pka] 7.89±0.35(predicted)

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[Uses] BaENR-IN-1 (Compound 5) is an inhibitor of Enoyl-Acyl Carrier Protein Reductase (ENR) (IC50= 7.7 μM). BaENR-IN-1 blocks the synthesis of fatty acids essential for bacterial growth by inhibiting the bacterial enzyme ENR. BaENR-IN-1 shows activity against bacteria[1].
[References] [1] Suresh K Tipparaju, et al. Design and synthesis of aryl ether inhibitors of the Bacillus anthracis enoyl-ACP reductase. ChemMedChem. 2008 Aug;3(8):1250-68. DOI:10.1002/cmdc.200800047

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