| Identification | Back Directory | [Name]
4-CYANOIMIDAZOLE | [CAS]
108257-41-6 | [Synonyms]
4-Cyanoimidazole
4-Methyl-5-cyanoimidazole
4(5)-cyano-5(4)-methylimidazole
5-Methylimidazole-4-carbonitrile
4-Methyl-1h-imidazole-5-carbonitrile
5-Methyl-1H-imidazole-4-carbonitrile
1H-IMidazole-4-carbonitrile, 5-Methyl-
1H-Imidazole-5-carbonitrile, 4-methyl- | [Molecular Formula]
C5H5N3 | [MOL File]
108257-41-6.mol | [Molecular Weight]
107.11 |
| Hazard Information | Back Directory | [Preparation]
A mixture of ethyl 4-imidazolecarboxylate (33 g) and ammonium hydroxide (250 mL) was heated to 100 C° in a sealed glass vessel for 1–7 days. The mixture was then cooled and the solid 4-imidazolecarboxamide 1443 was recovered by filtration in near quantitative yield and air dried. Dehydration was carried out by heating a solution of 4-imidazolecarboxamide 1443 (5 g) in PhPOCl2 (25 mL) at 80 C° for 12 h. The cooled reaction mixture was then poured over ice (200 mL) and adjusted to pH 11 with 50% aqueous sodium hydroxide. The 4-cyanoimidazole 1444 was isolated by extraction with ethyl acetate and concentration of the extracts in vacuo. |
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| Company Name: |
Energy Chemical
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| Tel: |
021-58432009 400-005-6266 |
| Website: |
http://www.energy-chemical.com |
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