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108437-64-5

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108437-64-5 Structure

108437-64-5 Structure
IdentificationBack Directory
[Name]

12-KETE
[CAS]

108437-64-5
[Synonyms]

12-KETE
12-OXOETE
GURBRQGDZZKITB-VXBMJZGYSA-N
12-OxoETE Lipid Maps MS Standard
12-OXO-5Z,8Z,10E,14Z-EICOSATETRAENOIC ACID
5,8,10,14-Eicosatetraenoic acid, 12-oxo-, (5Z,8Z,10E,14Z)-
[Molecular Formula]

C20H30O3
[MDL Number]

MFCD00216130
[MOL File]

108437-64-5.mol
[Molecular Weight]

318.45
Chemical PropertiesBack Directory
[storage temp. ]

Store at -20°C
[solubility ]

DMF: Miscible; DMSO: Miscible; Ethanol: Miscible; PBS pH 7.2: 0.8 mg/ml
Safety DataBack Directory
[Symbol(GHS) ]

Flame (GHS02)
GHS02
[Signal word ]

Danger
Hazard InformationBack Directory
[Uses]

12-OxoETE is synthesized by human platelets and Aplysia nervous tissue after incubation with arachidonic acid. Microsomal fractions of various tissues will reduce 12-oxoETE to 12(S)-HETE or a mixture of 12(S)- and 12(R)-HETE. 12-OxoETE induces a rapid, dose dependent increase of cytoplasmic free calcium via an Leukotriene B4 receptor or a common activation sequence.
[Definition]

ChEBI: An oxoicosatetraenoic acid having a 12-oxo group; and (5Z)-, (8Z), (10E)- and (14Z)-double bonds.
[IC 50]

Human Endogenous Metabolite
[storage]

Store at -20°C
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