| Identification | Back Directory | [Name]
1-CHLOROMETHYLPYRENE | [CAS]
1086-00-6 | [Synonyms]
1-CHLOROMETHYLPYRENE
1-(chloromethyl)-pyren
1-Chloromethylpyrene > | [Molecular Formula]
C17H11Cl | [MDL Number]
MFCD00962113 | [MOL File]
1086-00-6.mol | [Molecular Weight]
250.72 |
| Chemical Properties | Back Directory | [Melting point ]
144-145 °C | [Boiling point ]
434.1±14.0 °C(Predicted) | [density ]
1.321±0.06 g/cm3(Predicted) | [storage temp. ]
<0°C | [form ]
powder to crystal | [color ]
White to Orange to Green |
| Hazard Information | Back Directory | [Uses]
1-Chloromethylpyrene is an alkylating agent that enters the DNA double helix structure through intercalation, forms covalent bonds with electrophilic groups, resulting in DNA cross-linking, thereby inhibiting the proliferation of tumor cells[1]. | [References]
[1] Peck RM, et al., Mixed bifunctionality. 4. Antitumor activity of alkylating derivatives of polycyclic aromatic hydrocarbons as a function of structure and of vehicle. J Med Chem. 1972 Jan;15(1):68-70. DOI:10.1021/jm00271a018 |
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Energy Chemical
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