| Identification | Back Directory | [Name]
2-Amino-6-methythio-9-(2'-deoxy-2'-fluooro-beta-D-arabinofuranosyl)-9H-purine | [CAS]
109304-11-2 | [Synonyms]
2’-Deoxy-2’-fluoro-6-S-methyl-6-thio-ara-guanosine
9H-Purin-2-amine, 9-(2-deoxy-2-fluoro-β-D-arabinofuranosyl)-6-(methylthio)-
2-Amino-6-methythio-9-(2'-deoxy-2'-fluooro-beta-D-arabinofuranosyl)-9H-purine
2-Amino-6-methylthio-9-(2'-deoxy-2'-fluoro-beta-D-arabinofuranosyl)-9H-purine
2-Amino-6-methythio-9-(2’-deoxy-2’-fluooro-beta-D-arabinofuranosyl)-9H-purine | [Molecular Formula]
C11H14FN5O3S | [MOL File]
109304-11-2.mol | [Molecular Weight]
315.32 |
| Hazard Information | Back Directory | [Uses]
2’-Deoxy-2’-fluoro-6-S-Methyl-6-thio-ara-guanosine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1]. | [References]
[1] Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88. DOI:10.2174/138161212801227005 |
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