ChemicalBook--->CAS DataBase List--->109740-09-2

109740-09-2

109740-09-2 Structure

109740-09-2 Structure
IdentificationBack Directory
[Name]

2-PHENYL-2,5-DIHYDRO-4H-PYRAZOLO[3,4-C]QUINOLIN-4-ONE
[CAS]

109740-09-2
[Synonyms]

CHEMBL241987
CHEMBL241987,CHEMBL-241987
2-phenyl-5H-pyrazolo[3,4-c]quinolin-4-one
2-Phenyl-2H,4H,5H-pyrazolo[3,4-c]quinolin-4-one
2-PHENYL-2,5-DIHYDRO-4H-PYRAZOLO[3,4-C]QUINOLIN-4-ONE
[Molecular Formula]

C16H11N3O
[MDL Number]

MFCD07339082
[MOL File]

109740-09-2.mol
[Molecular Weight]

261.28
Chemical PropertiesBack Directory
[Melting point ]

>300 °C
[Boiling point ]

388.9±11.0 °C(Predicted)
[density ]

1.34±0.1 g/cm3(Predicted)
[pka]

12.07±0.20(Predicted)
Safety DataBack Directory
[Symbol(GHS) ]

Exclamation Mark (GHS07)
GHS07
[Signal word ]

Warning
[Hazard statements ]

H319-H302-H335-H315
[Precautionary statements ]

P264-P280-P305+P351+P338-P337+P313P-P264-P280-P302+P352-P321-P332+P313-P362-P264-P270-P301+P312-P330-P501
Hazard InformationBack Directory
[Uses]

A3AR antagonist 4 (Compd 1) is an A3AR antagonist, with Ki values of 30.8 nM (hA3) and 203 nM (hA1), repectively. A3AR antagonist 4 (Compd 1) can be used for the study of cerebral ischemia[1].
[References]

[1] Vittoria Colotta, et al. New 2-arylpyrazolo[3,4-c]quinoline derivatives as potent and selective human A3 adenosine receptor antagonists. Synthesis, pharmacological evaluation, and ligand-receptor modeling studies. J Med Chem. 2007 Aug 23;50(17):4061-74. DOI:10.1021/jm070123v
Spectrum DetailBack Directory
[Spectrum Detail]

2-PHENYL-2,5-DIHYDRO-4H-PYRAZOLO[3,4-C]QUINOLIN-4-ONE(109740-09-2)1HNMR
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