| Identification | Back Directory | [Name]
Lanosta-7,9(11),24-trien-26-oic acid, 3,22-bis(acetyloxy)-15-hydroxy-, (3α,15α,24E)- | [CAS]
110024-14-1 | [Synonyms]
Lanosta-7,9(11),24-trien-26-oic acid, 3,22-bis(acetyloxy)-15-hydroxy-, (3α,15α,24E)- | [Molecular Formula]
C34H50O7 | [MOL File]
110024-14-1.mol | [Molecular Weight]
570.76 |
| Hazard Information | Back Directory | [Uses]
Ganoderic acid Mk (GA-Mk) is a triterpenoid acid, that can be isolated from the mycelia of Ganoderma lucidum. Ganoderic acid Mk is efficiently anti-proliferative and can induce apoptosis of HeLa cells by mitochondria-mediated pathway. Ganoderic acid Mk can be used for cervical cancer research[1][2]. | [IC 50]
Caspase-3; Caspase-9 | [References]
[1] Liu R M, et al. Anti-proliferation and induced mitochondria-mediated apoptosis of ganoderic acid Mk from Ganoderma lucidum mycelia in cervical cancer HeLa cells[J]. Latin American Journal of Pharmacy, 2012, 31(1):43-50.
[2] Ding N, et al. Separation and determination of four ganoderic acids from dried fermentation mycelia powder of Ganoderma lucidum by capillary zone electrophoresis. J Pharm Biomed Anal. 2010 Dec 15;53(5):1224-30. DOI:10.1016/j.jpba.2010.07.025 |
|
|