| Identification | Back Directory | [Name]
1,3-Benzodioxole,5,5'-[(2R,3S)-2,3-dimethyl-1,4-butanediyl]bis-, rel- | [CAS]
110269-50-6 | [Synonyms]
Machilin A
1,3-Benzodioxole,5,5'-[(2R,3S)-2,3-dimethyl-1,4-butanediyl]bis-, rel- | [Molecular Formula]
C20H22O4 | [MOL File]
110269-50-6.mol | [Molecular Weight]
326.39 |
| Hazard Information | Back Directory | [Uses]
Machilin A is a lignan isolated from the methanolic extract of Phoebe bark. Machilin A inhibits melanin biosynthesis in B-16 mouse melanoma cells with an IC50 of 39.9 μM. | [References]
[1] Li G, et al.Melanin biosynthesis inhibitors from the bark of Machilus thunbergii. Biol Pharm Bull. 2003 Jul;26(7):1039-41. DOI:10.1248/bpb.26.1039 |
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