| Identification | Back Directory | [Name]
4-Pentynamide, N-[[4-[[(2-amino-9H-purin-6-yl)oxy]methyl]phenyl]methyl]- | [CAS]
1104822-07-2 | [Synonyms]
Alkyne-SNAP
N-[(4-{[(2-amino-7H-purin-6-yl)oxy]methyl}phenyl)methyl]pent-4-ynamide
4-Pentynamide, N-[[4-[[(2-amino-9H-purin-6-yl)oxy]methyl]phenyl]methyl]- | [Molecular Formula]
C18H18N6O2 | [MOL File]
1104822-07-2.mol | [Molecular Weight]
350.37 |
| Hazard Information | Back Directory | [Uses]
Alkyne-SNAP (compound 3) is an Alkyne-conjugated benzylguanine. The benzylguanine moiety reacts with the SNAP-tag, allowing irreversible and covalent labeling of SNAP fusion proteins with an additional alkyne functionality for further click chemistry conjugation[1]. | [References]
[1] Broichhagen J, et al. Orthogonal Optical Control of a G Protein-Coupled Receptor with a SNAP-Tethered Photochromic Ligand. ACS Cent Sci. 2015 Oct 28;1(7):383-93. DOI:10.1021/acscentsci.5b00260 |
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