| Identification | Back Directory | [Name]
3-(4-Fluorophenyl)-2,4-dioxo-1,2,3,4-tetrahydropyrimidine-5-carboxylic acid | [CAS]
1105193-80-3 | [Synonyms]
3-(4-Fluorophenyl)-2,4-dioxo-1,2,3,4-tetrahydropyrimidine-5-carboxylic acid
5-Pyrimidinecarboxylic acid, 1-(4-fluorophenyl)-1,2,3,6-tetrahydro-2,6-dioxo- | [Molecular Formula]
C11H7FN2O4 | [MDL Number]
MFCD16631563 | [MOL File]
1105193-80-3.mol | [Molecular Weight]
250.18 |
| Hazard Information | Back Directory | [Uses]
3-(4-Fluorophenyl)-2,4-dioxo-1,2,3,4-tetrahydropyrimidine-5-carboxylic acid is used in the discovery of pyrimidinediones as potential orally bioavailable axl inhibitor. The receptor tyrosine kinase Axl plays important roles in promoting cancer progression, metastasis, and drug resistance and has been identified as a promising target for anticancer therapeutics. |
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