| Identification | Back Directory | [Name]
Streptomyces pepsin inhibitor | [CAS]
11076-29-2 | [Synonyms]
Pepsidin c
Pepstatin AC
Streptomyces pepsin inhibitor
acetyl pepstatin|acetyl-pepstatin
N-Ac-L-Val-L-Val-Sta-L-Ala-Sta-OH
Ac-Val-val-4-amino-3-hydroxy-6-me-heptanoyl-Ala-4-amino-3-hydroxyl-6-me-heptanoic acid
Acetylvalylvalyl-4-amino-3-hydroxy-6-methylheptanoylalanyl-4-amino-3-hydroxyl-6-methylheptanoic acid
N-Acetyl-L-Val-L-Val-[(3S,4S)-4-amino*-3-hydroxy-6-methylheptanoyl]-L-Ala-[(1S)-1-[(1S)-2-carboxy-1-hydroxyethyl]-3-methylbutyl]NH2
L-Alaninamide, N-acetyl-L-valyl-L-valyl-(3S,4S)-4-amino-3-hydroxy-6-methylheptanoyl-N-[(1S)-1-[(1S)-2-carboxy-1-hydroxyethyl]-3-methylbutyl]-
L-Alaninamide, N-acetyl-L-valyl-L-valyl-(3S,4S)-4-amino-3-hydroxy-6-methylheptanoyl-N-[(1S)-1-[(1S)-2-carboxy-1-hydroxyethyl]-3-methylbutyl]- (9ci)
L-Valinamide, N-acetyl-L-valyl-N-[(1S,2S)-4-[[(1S)-2-[[(1S)-1-[(1S)-2-carboxy-1-hydroxyethyl]-3-methylbutyl]amino]-1-methyl-2-oxoethyl]amino]-2-hydroxy-1-(2-methylpropyl)-4-oxobutyl]-
L-Valinamide, N-acetyl-L-valyl-N-[4-[[2-[[1-(2-carboxy-1-hydroxyethyl)-3-methylbutyl]amino]-1-methyl-2-oxoethyl]amino]-2-hydroxy-1-(2-methylpropyl)-4-oxobutyl]-, [1S-[1R*,2R*,4[R*[R*(R*)]]]]- | [Molecular Formula]
C31H57N5O9 | [MDL Number]
MFCD00214071 | [MOL File]
11076-29-2.mol | [Molecular Weight]
643.81 |
| Hazard Information | Back Directory | [Uses]
Acetyl-pepstatin is a potent classical inhibitor of aspartic proteases (PRs) with XMRV PR and HIV-1 PR Ki values of 712 nM and 13 nM[1]. | [References]
[1] Matúz K, et al. Inhibition of XMRV and HIV-1 proteases by pepstatin A and acetyl-pepstatin. FEBS J. 2012;279(17):3276-3286. DOI:10.1111/j.1742-4658.2012.08714.x |
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