| Identification | Back Directory | [Name]
(N-ME-PHE7)-NEUROKININ B | [CAS]
110880-53-0 | [Synonyms]
L-Methioninamide, L-α-aspartyl-L-methionyl-L-histidyl-L-α-aspartyl-L-phenylalanyl-L-phenylalanyl-N-methyl-L-phenylalanylglycyl-L-leucyl- | [Molecular Formula]
C60H81N13O14S2 | [MDL Number]
MFCD18782503 | [MOL File]
110880-53-0.mol | [Molecular Weight]
1272.49 |
| Hazard Information | Back Directory | [Uses]
[MePhe7]-Neurokinin B is an neurokinin NK-3 receptor (NK3R) agonist with an IC50 value of 3 nM. [MePhe7]-Neurokinin B is a potential regulator of pulsatile gonadotropin-releasing hormone (GnRH) secretion via activation of the neurokinin-3 receptor (NK3R)[1]. | [IC 50]
NK3: 3 nM (IC50) | [References]
[1] Misu R, et, al. Structure-activity relationship study of tachykinin peptides for the development of novel neurokinin-3 receptor selective agonists. Bioorg Med Chem. 2013 Apr 15;21(8):2413-2417. DOI:10.1016/j.bmc.2013.01.036 |
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BOC Sciences
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1-631-485-4226; 16314854226 |
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https://www.bocsci.com |
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