| Identification | Back Directory | [Name]
N3-PEG13-OH | [CAS]
1111239-69-0 | [Synonyms]
N3-PEG13-OH
N3-PEG13-OH/3,6,9,12,15,18,21,24,27,30,33,36-Dodecaoxaoctatriacontan-1-ol, 38-azido- | [Molecular Formula]
C26H53N3O13 | [MDL Number]
MFCD31656905 | [MOL File]
1111239-69-0.mol | [Molecular Weight]
615.72 |
| Hazard Information | Back Directory | [Uses]
Azido-PEG12-alcohol is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. Azido-PEG12-alcohol is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups. | [IC 50]
PEGs | [References]
[1] Nalawansha DA, et al. PROTACs: An Emerging Therapeutic Modality in Precision Medicine. Cell Chem Biol. 2020;27(8):998-1007. DOI:10.1016/j.cell.2020.07.008 |
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