| Identification | Back Directory | [Name]
O-PHOSPHO-L-THREONINE | [CAS]
1114-81-4 | [Synonyms]
H-THR(PO3H2)-OH
O-Phosphothreonine
Threonine phosphate
O-PHOSPHO-L-THREONINE
L-THREONINE O-PHOSPHATE
Oxo-Phospho-L-Threonine
L-Threonine, O-phosphono-
(2S,3R)-O-Phosphothreonine
threoninium dihydrogen phosphate
L-Threonine dihydrogen phosphate
PHLOROGLUCINOL CARBOXYLIC ACID(RG)
PHOSPHOTHREONINE ANTIBODY INHIBITOR
(2S,3R)-2-Amino-3-phosphonooxybutanoic acid
L-2-AMINO-3-HYDROXYBUTANOIC ACID 3-PHOSPHATE
(s)-2-amino-3-hydroxybutanoic acid 3-phosphate
Phosphoric acid dihydrogen (1S,2R)-1-amino-1-carboxypropan-2-yl ester
L-Threonine O-phosphate, (S)-2-Amino-3-hydroxybutanoic acid 3-phosphate | [EINECS(EC#)]
214-217-5 | [Molecular Formula]
C4H10NO6P | [MDL Number]
MFCD00069578 | [MOL File]
1114-81-4.mol | [Molecular Weight]
199.1 |
| Chemical Properties | Back Directory | [Melting point ]
169 °C | [Boiling point ]
454.0±55.0 °C(Predicted) | [density ]
1.671±0.06 g/cm3(Predicted) | [storage temp. ]
-20°C | [solubility ]
NH4OH 1 M: 0.1 g/mL, clear, colorless | [form ]
A solid | [pka]
1.73±0.10(Predicted) | [color ]
white | [Optical Rotation]
-9.7°(C=0.01g/mI, H2O, 20°C, 589nm) | [BRN ]
1727078 | [InChI]
1S/C4H10NO6P/c1-2(3(5)4(6)7)11-12(8,9)10/h2-3H,5H2,1H3,(H,6,7)(H2,8,9,10)/t2-,3+/m1/s1 | [InChIKey]
USRGIUJOYOXOQJ-GBXIJSLDSA-N | [SMILES]
C[C@@H](OP(O)(O)=O)[C@H](N)C(O)=O |
| Hazard Information | Back Directory | [Uses]
O-Phospho-L-threonine is a threonine derivative[1]. | [Definition]
ChEBI: O-phospho-L-threonine is a L-threonine derivative phosphorylated at the side-chain hydroxy function. It has a role as an Escherichia coli metabolite. It is a L-threonine derivative, a non-proteinogenic L-alpha-amino acid and an O-phosphoamino acid. It is a conjugate acid of an O-phosphonato-L-threonine(2-). | [Biochem/physiol Actions]
O-Phospho-L-threonine is an amino acid derivative. | [IC 50]
Human Endogenous Metabolite | [Purification Methods]
Dissolve the phosphate in the minimum volume of H2O, add charcoal, stir for a few minutes, filter and apply onto a column of Dowex 50W (H+ form), then elute with 2N HCl. Evaporate the eluates under reduced pressure whereby the desired fraction produces crystals of the phosphate which can be recrystallised from H2O/MeOH mixtures and the crystals are then dried in vacuo over P2O5 at ~80o. [de Verdier Acta Chem Scand 7 196 1953, Beilstein 4 IV 3175.] | [References]
[1] Luckose F, et al. Effects of amino acid derivatives on physical, mental, and physiological activities. Crit Rev Food Sci Nutr. 2015;55(13):1793-1144. DOI:10.1080/10408398.2012.708368 |
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