| Identification | Back Directory | [Name]
Ketene Dimethyl Thioacetal Monoxide | [CAS]
111674-84-1 | [Synonyms]
Ketene Dimethyl Thioacetal Monoxide | [Molecular Formula]
C4H8O2S-2 | [MDL Number]
MFCD16876616 | [MOL File]
111674-84-1.mol | [Molecular Weight]
120.17 |
| Chemical Properties | Back Directory | [Boiling point ]
145-150 °C/27 mmHg | [solubility ]
sol most common organic solvents (i.e. THF, Et2O, DME, CH2Cl2, MeCN, t-BuOH, CS2, benzene) |
| Hazard Information | Back Directory | [Uses]
Ketene Dimethyl Thioacetal Monoxide is used for formylmethyl synthon used as an acceptor in conjugate addition reactions.
| [Synthesis Reference(s)]
1.Herrmann, J. L.; Kieczykowski, G. R.; Romanet, R. F.; Wepplo, P. J.; Schlessinger, R. H. TL 1973, 4711.
2. Kaya, R.; Beller, N. R. JOC 1981, 46, 196. | [Synthesis]
Ketene Dimethyl Thioacetal Monoxide is synthesized from glyoxylic acid in six steps.1A shorter synthesis involving a two-pot reaction sequence has been developed.2
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