| Identification | Back Directory | [Name]
CIS CIS-MUCONIC ACID | [CAS]
1119-72-8 | [Synonyms]
4Z)-2
cis,cis-Muconic acid,98%
cis,cis-Muconic acid, 98% 2.5GR
(2Z,4Z)-2,4-Hexadienedioic acid
(2Z,4Z)-hexa-2,4-dienedioic acid
cis,cis-Muconic acid
cis,cis-Muconic acid >=97.0% (HPLC) | [Molecular Formula]
C6 H6 O4 | [MDL Number]
MFCD00085266 | [MOL File]
1119-72-8.mol | [Molecular Weight]
142.11 |
| Chemical Properties | Back Directory | [Appearance]
yellow-beige crystalline powder | [Melting point ]
194-195 °C(lit.)
| [Boiling point ]
179.65°C (rough estimate) | [density ]
1.1712 (rough estimate) | [refractive index ]
1.4434 (estimate) | [storage temp. ]
Inert atmosphere,2-8°C | [form ]
Crystalline Powder | [pka]
3.57±0.25(Predicted) | [color ]
Yellow-beige | [BRN ]
1722246 | [InChI]
InChI=1S/C6H6O4/c7-5(8)3-1-2-4-6(9)10/h1-4H,(H,7,8)(H,9,10)/b3-1-,4-2- | [InChIKey]
TXXHDPDFNKHHGW-CCAGOZQPSA-N | [SMILES]
C(O)(=O)/C=C\C=C/C(O)=O | [CAS DataBase Reference]
1119-72-8 |
| Hazard Information | Back Directory | [Chemical Properties]
yellow-beige crystalline powder | [Definition]
ChEBI: The cis,cis-isomer of muconic acid. It is produced during the degradation of chlorobenzene by bacteria like Bacillus. | [Uses]
cis,cis-Muconic acid, a metabolic intermediate of Klebsiella pneumonia, can be converted to adipic acid and terephthalic acid, which are important monomers of synthetic polymers. cis,cis-Muconic acid is also a biochemical material that can be used for the production of various plastics and polymers and is particularly gaining attention as an adipic acid precursor for the synthesis of nylon-6,6[1][2]. | [General Description]
cis,cis-Muconic acid is a naturally-occurring organic acid. It is also referred as 2E,4E-hexa-2,4-dienedioic acid. It is used in the manufacture of several widely-used consumer plastics. Its microbial production via extending shikimate pathway has been reported. | [IC 50]
Microbial Metabolite; Human Endogenous Metabolite | [References]
[1] Jung HM, et al. Metabolic engineering of Klebsiella pneumoniae for the production of cis,cis-muconic acid. Appl Microbiol Biotechnol. 2015;99(12):5217-5225. DOI:10.1007/s00253-015-6442-3
[2] Shin WS, et al. Characterization of a non-phosphotransferase system for cis,cis-muconic acid production in Corynebacterium glutamicum. Biochem Biophys Res Commun. 2018;499(2):279-284. DOI:10.1016/j.bbrc.2018.03.146 |
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