| Identification | Back Directory | [Name]
D-Aspartic Acid diethyl ester hydrochloride | [CAS]
112018-26-5 | [Synonyms]
D-Asp-Oet.2Hcl
D-Asp(oet)-Oet.Hcl
D-Aspartic Acid diet
H-D-ASP(OET)-OET·HCL
(R)-Diethyl 2-aminosuccinate hydrochloride
D-Aspartic Acid diethyl ester hydrochloride
iethyl(2R)-2-aminobutanedioate,hydrochloride
diethyl (2R)-2-aminobutanedioate,hydrochloride
D-Aspartic acid α,β-diethyl ester hydrochloride
1,4-diethyl (2R)-2-aminobutanedioate hydrochloride
D-Aspartic Acid diethyl ester hydrochloride USP/EP/BP | [Molecular Formula]
C8H16ClNO4 | [MDL Number]
MFCD11225843 | [MOL File]
112018-26-5.mol | [Molecular Weight]
225.67 |
| Hazard Information | Back Directory | [Synthesis]
Acetyl chloride (54.6 mL, 0.75 mol) was slowly added dropwise to ethanol (316 mL) at 0-5 °C. After the dropwise addition was completed, the ice bath was removed and the reaction solution was continued to be stirred at room temperature for 30 min. Subsequently, D-aspartic acid (19.1, 25 g, 0.188 mol) was added to the reaction system. The reaction mixture was heated to reflux for 2 hours. Upon completion of the reaction, the reaction solution was concentrated in vacuum and dried under high vacuum (0.4 mmHg) overnight to afford compound 19.2 (42 g, 99% yield) as a white solid, which can be used in subsequent reactions without further purification. | [References]
[1] Patent: WO2007/56056, 2007, A2. Location in patent: Page/Page column 75-76 |
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