| Identification | Back Directory | [Name]
Pyrithione | [CAS]
1121-30-8 | [Synonyms]
PTO
SQ-2113
PYRITHIONE
N-HYDROXYPYRIDINE-2-THIONE
2-PYRIDINETHIONE,1-HYDROXY-
N-HYDROXYPYRIDINE-(1H)-THIONE
1-Hydroxypyridine-2(1H)-Thione
1-hydroxyl-1H-pyridine-2-thione
2(1H)-Pyridinethione, 1-hydroxy- | [EINECS(EC#)]
214-328-9 | [Molecular Formula]
C5H5NOS | [MDL Number]
MFCD00059791 | [MOL File]
1121-30-8.mol | [Molecular Weight]
127.164 |
| Chemical Properties | Back Directory | [Melting point ]
68°C | [Boiling point ]
253.8±23.0 °C(Predicted) | [density ]
1.255 (estimate) | [refractive index ]
1.5480 (estimate) | [storage temp. ]
2-8°C | [form ]
solid | [pka]
4.70±0.20(Predicted) |
| Hazard Information | Back Directory | [Description]
The sodium salt of N-hydroxy-2-pyridinethiones has a
germicidal activity againts yeasts and fungi. Sodium
omadine is a 40% aqueous solution of sodium
pyrithione. | [Uses]
It is used in the metallurgical industry as
a component of water-based metalwork fluids, of
aceto-polyvinyl lattices, water-based printer's ink,
lubrieant for synthetie fibers and anti-dandruff shampoos.
A case was reported in a metallurgie worker. | [Definition]
ChEBI: A pyridinethione that is pyridine-2(1H)-thione in which the hydrogen attached to the nitrogen is replaced by a hydroxy group. It is a Zn2+ ionophore; the zinc salt is used as an antifungal and antibacterial agent. | [Synthesis Reference(s)]
Journal of the American Chemical Society, 72, p. 4362, 1950 DOI: 10.1021/ja01166a008 |
|
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Sigma-Aldrich
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parabiochem
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www.parabiochem.cn |
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