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112529-37-0

112529-37-0 Structure

112529-37-0 Structure
IdentificationBack Directory
[Name]

4-O-Methylepisappanol
[CAS]

112529-37-0
[Synonyms]

4-O-Methylepisappanol
2H-1-Benzopyran-3,7-diol, 3-[(3,4-dihydroxyphenyl)methyl]-3,4-dihydro-4-methoxy-, (3R,4R)-
[Molecular Formula]

C17H18O6
[MOL File]

112529-37-0.mol
[Molecular Weight]

318.32
Chemical PropertiesBack Directory
[Boiling point ]

564.0±50.0 °C(Predicted)
[density ]

1.48±0.1 g/cm3(Predicted)
[pka]

9.68±0.60(Predicted)
Hazard InformationBack Directory
[Uses]

4-O-Methylepisappanol (compound 9) is nature product that could be isolated from heartwood of Caesalpinia sappan. 4-O-Methylepisappanol is a potent neuraminidase inhibitor on the surface of influenza viruses with IC50 values of 42.8, 63.2, and 63.2 μM for A/Chicken/Korea/MS96/96 [H9N2], A/PR/8/34 [H1N1], and A/Hong Kong/8/68 [H3N2], respectively[1].
[References]

[1] Jeong HJ, et, al. Homoisoflavonoids from Caesalpinia sappan displaying viral neuraminidases inhibition. Biol Pharm Bull. 2012;35(5):786-90. DOI:10.1248/bpb.35.786
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