| Identification | Back Directory | [Name]
[(E)-(5-nitrofuran-2-yl)methylideneamino]urea | [CAS]
112574-44-4 | [Synonyms]
[(E)-(5-nitrofuran-2-yl)methylideneamino]urea
(E)-2-((5-Nitrofuran-2-yl)methylene)hydrazinecarboxamide
(E)-2-((5-nitrofuran-2-yl)methylene)hydrazine-1-carboxamide | [Molecular Formula]
C6H6N4O4 | [MOL File]
112574-44-4.mol | [Molecular Weight]
198.14 |
| Hazard Information | Back Directory | [Uses]
(E)-Nitrofurazone ((E)-Nitrofural) is a topical broad-spectrum antibacterial agent effective against both Gram-negative and Gram-positive bacteria. (E)-Nitrofurazone also possesses antiprotozoal and antiparasitic activities. (E)-Nitrofurazone is commonly used in the research of superficial wounds, burns, skin infections, pyoderma, infectious skin diseases, trypanosomiasis, and acute bacillary dysentery[1][2]. | [Definition]
ChEBI: Nitrofurazone is a semicarbazone resulting from the formal condensation of semicarbazide with 5-nitrofuraldehyde. A broad spectrum antibacterial drug, although with little activity against Pseudomonas species, it is used as a local application for burns, ulcers, wounds and skin infections. It has a role as an antibacterial drug. It is a semicarbazone and a nitrofuran antibiotic. | [References]
[1] Kolev I N, et al. A new FTIR-based technique in the polymorphic analysis of Nitrofural[J]. Journal of Molecular Structure, 2021, 1233: 130098.
[2] Nitrofural (nitrofurazone). IARC Monogr Eval Carcinog Risks Hum. 1990;50:195-209. PMID: 2292799; PMCID: PMC7681543. |
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